| Cubs | ||||
| Schedule: | ||||
| Home | Away | Location | Date | Time |
| Cubs | Athletics | Key Bank Field | 05/08/2021 | 4:00 PM |
| Nationals | Cubs | Key Bank Field | 05/11/2021 | 5:45 PM |
| Cubs | Rockies | Key Bank Field | 05/18/2021 | 5:45 PM |
| Twins | Cubs | Key Bank Field | 05/22/2021 | 1:30 PM |
| Athletics | Cubs | Key Bank Field | 05/25/2021 | 5:45 PM |
| Cubs | Nationals | Key Bank Field | 05/27/2021 | 5:45 PM |
| Rockies | Cubs | Key Bank Field | 06/05/2021 | 4:00 PM |
| Cubs | Twins | Key Bank Field | 06/08/2021 | 5:45 PM |
| Nationals | Cubs | NBT Field | 06/12/2021 | 3:30 PM |
| Cubs | Athletics | NBT Field | 06/15/2021 | 6:00 PM |
| Rockies | Cubs | Key Bank Field | 06/22/2021 | 5:45 PM |
| Cubs | Twins | NBT Field | 06/24/2021 | 6:00 PM |
League scheduling software generated 2021.04.22 at 15:11:46 EDT